Tetuin

Tetuin
	Tetuin source ↗
Names
	IUPAC name 6-(β-D-Glucopyranosyloxy)-5,7-dihydroxyflavone
	Systematic IUPAC name 5,7-Dihydroxy-2-phenyl-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4H-1-benzopyran-4-one
	Other names Baicalein 6-glucoside; Baicalein 6-O-glucoside
Identifiers
CAS Number	28279-72-3 Y;
3D model (JSmol)	Interactive image;
ChemSpider	58802100 Y;
PubChem CID	5321896;
CompTox Dashboard (EPA)	DTXSID20498465 ;
	InChI InChI=1S/C21H20O10/c22-8-14-16(25)18(27)19(28)21(30-14)31-20-11(24)7-13-15(17(20)26)10(23)6-12(29-13)9-4-2-1-3-5-9/h1-7,14,16,18-19,21-22,24-28H,8H2/t14-,16-,18+,19-,21+/m1/s1 Key: WTYYPLMAODUDGW-QOUKUZOOSA-N;
	SMILES C1=CC=C(C=C1)C2=CC(=O)C3=C(C(=C(C=C3O2)O)OC4C(C(C(C(O4)CO)O)O)O)O;
Properties
Chemical formula	C21H20O10
Molar mass	432.37 g/mol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Y verify (what is YN ?) Infobox references

Tetuin is the name originally allocated to a chemical constituent of the seeds of Oroxylum indicum, the Indian trumpetflower,¹ known as टेटु tetu in Marathi. The original authors identified this chemical as the 6-O-glucoside of baicalein, a flavone, a type of flavonoid. Their identification was probably incorrect, as subsequent authors were able to demonstrate that baicalein 6-O-glucoside has different properties to the original tetuin from O. indicum seeds,² and were unable to find baicalein glycosides in the seeds.³ Nevertheless, modern authors have used the name tetuin as a trivial name for baicalein 6-O-glucoside.⁴

References

Mehta C. R. and Mehta T. P., 1959 Journal of the Indian Chemical Society 36:468
Mezey-Vándor, Gabriella; Farkas, Loránd; Kanzel, Ida; Nógrádi, Mihály (May 1980). "Synthese von Baicalin und einiger anderer Baicalein-glycoside". Chemische Berichte. 113 (5): 1945–1949.
Ramachandran Nair, A.G.; Joshi, B.S. (October 1979). "Oroxindin—A new flavone glucuronide from Oroxylum indicum Vent" (PDF). Proceedings of the Indian Academy of Sciences - Chemical Sciences. 88: 323–327. Retrieved 11 March 2026.
Pathak, Prateek; Novak, Jurica; Naumovich, Vladislav; Grishina, Maria; Balkrishna, Acharya; Sharma, Niti; Sharma, Vinay; Vladimir, Potemkin; Verma, Amita (2020). "Polyphenolic rich extract of Oroxylum indicum alleviate β - glucuronidase activity via down - regulate oxidative stress: Experimental and computational studies". Biocatalysis and Agricultural Biotechnology. 29 101804. doi:10.1016/j.bcab.2020.101804.

[1] Mehta C. R. and Mehta T. P., 1959 Journal of the Indian Chemical Society 36:468

[2] Mezey-Vándor, Gabriella; Farkas, Loránd; Kanzel, Ida; Nógrádi, Mihály (May 1980). "Synthese von Baicalin und einiger anderer Baicalein-glycoside". Chemische Berichte. 113 (5): 1945–1949.

[3] Ramachandran Nair, A.G.; Joshi, B.S. (October 1979). "Oroxindin—A new flavone glucuronide from Oroxylum indicum Vent" (PDF). Proceedings of the Indian Academy of Sciences - Chemical Sciences. 88: 323–327. Retrieved 11 March 2026.

[4] Pathak, Prateek; Novak, Jurica; Naumovich, Vladislav; Grishina, Maria; Balkrishna, Acharya; Sharma, Niti; Sharma, Vinay; Vladimir, Potemkin; Verma, Amita (2020). "Polyphenolic rich extract of Oroxylum indicum alleviate β - glucuronidase activity via down - regulate oxidative stress: Experimental and computational studies". Biocatalysis and Agricultural Biotechnology. 29 101804. doi:10.1016/j.bcab.2020.101804.

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