Article · Wikipedia archive · Last revised Jul 5, 2026

Tetrindole

Tetrindole was a drug candidate that functions by reversibly inhibiting monoamine oxidase A; it was first synthesized in Moscow in the early 1990s. Tetrindole is similar in its chemical structure to pirlindole (Pyrazidol), and metralindole.

Last revised
Jul 5, 2026
Read time
≈ 1 min
Length
135 w
Citations
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Source
Wikipedia ↗
Tetrindole
Clinical data
ATC code
  • None
Identifiers
  • 2,3,3a,4,5,6-hexahydro-8-cyclohexyl-1H-pyrazino[3,2,1-j,k]carbazole
CAS Number
PubChem CID
ChemSpider
UNII
ChEBI
ChEMBL
Chemical and physical data
FormulaC20H26N2
Molar mass294.442 g·mol−1
3D model (JSmol)
  • C1CCC(CC1)C2=CC3=C(C=C2)N4CCNC5C4=C3CCC5
  • InChI=1S/C20H26N2/c1-2-5-14(6-3-1)15-9-10-19-17(13-15)16-7-4-8-18-20(16)22(19)12-11-21-18/h9-10,13-14,18,21H,1-8,11-12H2 checkY
  • Key:AUXCHYJDVJZEPG-UHFFFAOYSA-N checkY
 X markNcheckY (what is this?)  (verify)

Tetrindole was a drug candidate that functions by reversibly inhibiting monoamine oxidase A; it was first synthesized in Moscow in the early 1990s.1 Tetrindole is similar in its chemical structure to pirlindole (Pyrazidol), and metralindole.2

See also

See also

References

References

  1. Medvedev AE, Kirkel AA, Kamyshanskaya NS, Moskvitina TA, Axenova LN, Gorkin VZ, et al. (January 1994). "Monoamine oxidase inhibition by novel antidepressant tetrindole". Biochemical Pharmacology. 47 (2): 303–8. doi:10.1016/0006-2952(94)90021-3. PMID 8304974.
  2. Ramsay RR, Gravestock MB (March 2003). "Monoamine oxidases: to inhibit or not to inhibit". Mini Reviews in Medicinal Chemistry. 3 (2): 129–36. doi:10.2174/1389557033405287. PMID 12570845.