TAS2R19

TAS2R19
Identifiers
Aliases	TAS2R19, MSTP058, T2R19, T2R23, T2R48, TAS2R23, TAS2R48, taste 2 receptor member 19
External IDs	OMIM: 613961; MGI: 2681304; HomoloGene: 89250; GeneCards: TAS2R19; OMA:TAS2R19 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	11,022,620 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	132,755,125 bp
RNA expression pattern
	Top expressed in
	testicle; ; corpus callosum; ; Achilles tendon; ; epithelium of colon; ; tonsil; ; left ovary; ; cerebellar cortex; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; stromal cell of endometrium;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity; bitter taste receptor activity;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	detection of chemical stimulus involved in sensory perception of bitter taste; signal transduction; response to stimulus; sensory perception of taste; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	259294
	353165
	ENSG00000212124
	ENSMUSG00000053217
	P59542
	Q7TQA8
	NM_176888
	NM_181276
	NP_795369
	NP_851793
	Wikidata
View/Edit Human	View/Edit Mouse

Taste receptor type 2 member 19 is a protein that in humans is encoded by the TAS2R19 gene.⁵ It seems to be involved in the perception of salt and bitter tastes.

References

GRCh38: Ensembl release 89: ENSG00000212124 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000053217 – Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: TAS2R19 taste receptor, type 2, member 19".

Further reading

Margolskee RF (2002). "Molecular mechanisms of bitter and sweet taste transduction". J. Biol. Chem. 277 (1): 1–4. doi:10.1074/jbc.R100054200. PMID 11696554.
Montmayeur JP, Matsunami H (2002). "Receptors for bitter and sweet taste". Curr. Opin. Neurobiol. 12 (4): 366–71. doi:10.1016/S0959-4388(02)00345-8. PMID 12139982. S2CID 37807140.
Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat. Genet. 32 (3): 397–401. doi:10.1038/ng1014. PMID 12379855. S2CID 20426192.
Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ (2003). "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways". Cell. 112 (3): 293–301. doi:10.1016/S0092-8674(03)00071-0. PMID 12581520. S2CID 718601.
Fischer A, Gilad Y, Man O, Pääbo S (2005). "Evolution of bitter taste receptors in humans and apes". Mol. Biol. Evol. 22 (3): 432–6. doi:10.1093/molbev/msi027. PMID 15496549.
Go Y, Satta Y, Takenaka O, Takahata N (2006). "Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates". Genetics. 170 (1): 313–26. doi:10.1534/genetics.104.037523. PMC 1449719. PMID 15744053.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000212124 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000053217 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: TAS2R19 taste receptor, type 2, member 19".

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See also

References

Further reading