Sutphin is a surname almost exclusively found in the United States. It is an Americanized form of the Dutch surname Zutphen or Van Zutphen, from the place-name Zutphen (used for residents),1 meaning "south fen".
Notable persons with the name include:
- Dudley Sutphin (1875–1926), American lawyer and tennis player
- William H. Sutphin (1887–1970), American politician
- Beverly Sutphin, character in John Waters' 1994 film Serial Mom