Siminina, was a Roman era civitas of the Roman province of Africa Proconsularis. The ancient city is tentatively identified with ruins at Bir-El-Djedidi, Tunisia.
The city was also the seat of an ancient Christian bishopric, suffragan of Archdiocese of Carthage. Only two bishops of Siminina are documented
- Deuterium was present at the Council of Carthage (484) called by the Vandal king Huneric.
- Giuniano intervened in the Council of Carthage (525).
Today Siminina survives as a titular bishopric.
From 17 December 2024 the titular bishop is Iyad Twal, auxiliary bishop of the Latin Patriarchate of Jerusalem.
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