Article · Wikipedia archive · Last revised Jun 30, 2026

RNR2

RNR2 is a human ribosomal DNA gene located on Chromosome 14. Tandem copies of this gene form one of five nucleolus organizer regions in the human genome, they are located on the chromosomes 13 (RNR1), 14 (RNR2), 15 (RNR3), 21 (RNR4), 22 (RNR5). Each gene cluster contains 30–40 copies and encodes a 45S RNA product that is then processed to form 18S, 5.8S and 28S rRNA.

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Jun 30, 2026
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RNR2
Identifiers
AliasesRNR2, RNA, ribosomal 45S cluster 2
External IDsOMIM: 180451; GeneCards: RNR2; OMA:RNR2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez

6053

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed search1n/a
Wikidata
View/Edit Human

RNR2 (RNA, ribosomal 45S cluster 22) is a human ribosomal DNA gene located on Chromosome 14. Tandem copies of this gene form one of five nucleolus organizer regions in the human genome, they are located on the chromosomes 13 (RNR1), 14 (RNR2), 15 (RNR3), 21 (RNR4), 22 (RNR5).32 Each gene cluster contains 30–40 copies and encodes a 45S RNA product that is then processed to form 18S, 5.8S and 28S rRNA.2

References

References

  1. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  2. "Entrez Gene: RNR1 RNA, ribosomal 1". Retrieved 2024-08-01.
  3. Schmidt O (2017). Fritsche O (ed.). Genetik und Molekularbiologie [Genetics and molecular biology]. Kompaktwissen Biologie (in German). Berlin, Heidelberg: Springer-Verlag Berlin Heidelberg. doi:10.1007/978-3-662-50274-7. ISBN 978-3-662-50273-0.
Further reading

Further reading

  • Nucleolus organizer regions are chromosomal regions crucial for the formation of the nucleolus, located on the short arms of the acrocentric chromosomes 13, 14, 15, 21 and 22