RNF122

RNF122
Identifiers
Aliases	RNF122, ring finger protein 122
External IDs	MGI: 1916117; HomoloGene: 11717; GeneCards: RNF122; OMA:RNF122 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	33,567,128 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	31,621,510 bp
RNA expression pattern
	Top expressed in
	left uterine tube; ; right ovary; ; left ovary; ; muscle of thigh; ; ganglionic eminence; ; right auricle of heart; ; gastrocnemius muscle; ; right uterine tube; ; granulocyte; ; upper lobe of left lung;
	Top expressed in
	zygote; ; hand; ; Rostral migratory stream; ; maxillary prominence; ; mandibular prominence; ; primary oocyte; ; genital tubercle; ; superior cervical ganglion; ; secondary oocyte; ; ganglionic eminence;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	ubiquitin protein ligase activity; metal ion binding; protein binding;
Cellular component	integral component of membrane; Golgi apparatus; membrane; endoplasmic reticulum; endomembrane system; cytoplasm;
Biological process	proteasome-mediated ubiquitin-dependent protein catabolic process; protein polyubiquitination; protein ubiquitination; negative regulation of mitochondrial membrane potential; positive regulation of apoptotic process; protein autoubiquitination;
	Sources:Amigo / QuickGO
Orthologs
	79845
	68867
	ENSG00000133874
	ENSMUSG00000039328
	Q9H9V4
	Q8BP31
	NM_024787
	NM_175136; NM_001368373; NM_001368374; NM_001368375
	NP_079063
	NP_780345; NP_001355302; NP_001355303; NP_001355304
	Wikidata
View/Edit Human	View/Edit Mouse

RING finger protein 122 is a protein that in humans is encoded by the RNF122 gene.⁵

The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions.⁵

References

GRCh38: Ensembl release 89: ENSG00000133874 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000039328 – Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: RNF122 ring finger protein 122".

Further reading

Koyama K, Sudo K, Nakamura Y (1995). "Isolation of 115 human chromosome 8-specific expressed-sequence tags by exon amplification". Genomics. 26 (2): 245–53. doi:10.1016/0888-7543(95)80207-3. PMID 7601449.
Saurin AJ, Borden KL, Boddy MN, Freemont PS (1996). "Does this have a familiar RING?". Trends Biochem. Sci. 21 (6): 208–14. doi:10.1016/s0968-0004(96)80017-x. PMID 8744354.
Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. Bibcode:2000PNAS...97.3491D. doi:10.1073/pnas.97.7.3491. PMC 16267. PMID 10737800.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Wang L, Gao X, Gao P, et al. (2006). "Cell-based screening and validation of human novel genes associated with cell viability". Journal of Biomolecular Screening. 11 (4): 369–76. doi:10.1177/1087057106286654. PMID 16751333.
Wang L, Shi TP, Wang L, et al. (2006). "[Cloning, expression and subcellular localization of a novel human gene-RNF122]". Beijing da Xue Xue Bao. 38 (3): 239–43. PMID 16778963.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000133874 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000039328 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: RNF122 ring finger protein 122".

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