Article · Wikipedia archive · Last revised Jul 6, 2026

Proquazone

Proquazone is a nonsteroidal anti-inflammatory drug, known as an NSAID.

Last revised
Jul 6, 2026
Read time
≈ 1 min
Length
154 w
Citations
5
Source
Wikipedia ↗
Proquazone
Clinical data
ATC code
Identifiers
  • 1-isopropyl-7-methyl-4-phenylquinazolin-2(1H)-one
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.041.079
Chemical and physical data
FormulaC18H18N2O
Molar mass278.355 g·mol−1
3D model (JSmol)
  • CC1=CC2=C(C=C1)C(=NC(=O)N2C(C)C)C3=CC=CC=C3
  • InChI=1S/C18H18N2O/c1-12(2)20-16-11-13(3)9-10-15(16)17(19-18(20)21)14-7-5-4-6-8-14/h4-12H,1-3H3 ☒N
  • Key:JTIGKVIOEQASGT-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Proquazone is a nonsteroidal anti-inflammatory drug, known as an NSAID.1

Uses

Proquazone is used to treat rheumatoid arthritis, osteoarthritis and ankylosing spondylitis.1 It has been trialed for use as pain relief for tension headaches.2

The recommended adult dose is around 450mg.1

Side Effects

Often, use of Proquazone is associated with diarrhea (up to 30% of the time).1

References

References

  1. Clissold SP, Beresford R (May 1987). "Proquazone. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in rheumatic diseases and pain states". Drugs. 33 (5): 478–502. doi:10.2165/00003495-198733050-00004. PMID 3297621. S2CID 195697106.
  2. DiSerio FJ, Friedman AP, Parno J, Singer JM (May 1985). "Proquazone for tension headache--a multicenter trial". Headache. 25 (3): 127–133. doi:10.1111/j.1526-4610.1985.hed2503127.x. PMID 3891682. S2CID 9283866.