Article · Wikipedia archive · Last revised Jun 16, 2026

Propargite

Propargite is a pesticide used to kill mites. It acts through inhibition of mitochondrial ATP synthase, and is in IRAC group 12C. Symptoms of excessive exposure are eye and skin irritation, and possibly sensitization. It is highly toxic to amphibians, fish, and zooplankton, as well as having potential carcinogenity.

Last revised
Jun 16, 2026
Read time
≈ 1 min
Length
259 w
Citations
5
Source
Wikipedia ↗
Propargite12
Skeletal formula
source ↗
Space-filling model
source ↗
Names
IUPAC name
2-(4-tert-butylphenoxy)cyclohexyl prop-2-yne-1-sulfonate
Other names
Omite, Comite, Uniroyal D014
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.017.279
KEGG
UNII
  • InChI=1S/C19H26O4S/c1-5-14-21-24(20)23-18-9-7-6-8-17(18)22-16-12-10-15(11-13-16)19(2,3)4/h1,10-13,17-18H,6-9,14H2,2-4H3
  • O=S(OCC#C)OC2CCCCC2Oc1ccc(cc1)C(C)(C)C
Properties
C19H26O4S
Molar mass 350.47 g·mol−1
Appearance dark amber viscous liquid
Density 1.10 g/cm3
0.5 ppm
Solubility miscible in organic solvents
Hazards
Safety data sheet (SDS) Cornell University
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Propargite (IUPAC name 2-(4-tert-butylphenoxy)cyclohexyl prop-2-yne-1-sulfonate, trade names Mitex, Omite and Comite) is a pesticide used to kill mites (an acaricide).2 It acts through inhibition of mitochondrial ATP synthase, and is in IRAC group 12C.3 Symptoms of excessive exposure are eye and skin irritation, and possibly sensitization. It is highly toxic to amphibians, fish, and zooplankton, as well as having potential carcinogenity.4

References

References

  1. Lide, David R. (1998), Handbook of Chemistry and Physics (87 ed.), Boca Raton, Florida: CRC Press, pp. 3–482, ISBN 978-0-8493-0594-8
  2. "propargite (Omite, Comite) Chemical Fact Sheet 9/86". Cornell University. 1986-09-30. Retrieved 2009-12-02.
  3. Kadir, Habsah A.; Knowles, Charles O. (1 June 1991). "Inhibition of ATP Dephosphorylation by Acaricides with Emphasis on the Anti-ATPase Activity of the Carbodiimide Metabolite of Diafenthiuron". Journal of Economic Entomology. 84 (3): 801–805. doi:10.1093/jee/84.3.801. PMID 1832178.
  4. "Integrated Risk Information System". 2013-03-15.{{cite web}}: CS1 maint: deprecated archival service (link)

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2011.2087/epdf

External links
  • Propargite in the Pesticide Properties DataBase (PPDB)