Article · Wikipedia archive · Last revised Jul 27, 2026

Phenamidine

Phenamidine is an antiprotozoal drug of the amidine class used in veterinary medicine. It is used to treat Babesia infection (babesiosis) dogs, horses, and cattle. Because the drug causes frequent allergic reactions, it is usually combined with an antihistamine.

Last revised
Jul 27, 2026
Read time
≈ 1 min
Length
115 w
Citations
4
Source
Wikipedia ↗
Phenamidine
Clinical data
Trade namesOxopirvedine
Other names4,4'-Diamidinodiphenyl ether; 4,4'-Oxydibenzamidine
ATCvet code
Identifiers
  • 4,4’-Oxydibenzenecarboximidamide
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.002.692
Chemical and physical data
FormulaC14H14N4O
Molar mass254.293 g·mol−1
3D model (JSmol)
Melting point215 to 216 °C (419 to 421 °F) 1
  • O(c1ccc(C(=[N@H])N)cc1)c2ccc(cc2)C(=[N@H])N
  • InChI=1S/C14H14N4O/c15-13(16)9-1-5-11(6-2-9)19-12-7-3-10(4-8-12)14(17)18/h1-8H,(H3,15,16)(H3,17,18)
  • Key:DMABBVCVVXMJDH-UHFFFAOYSA-N

Phenamidine is an antiprotozoal drug of the amidine class used in veterinary medicine. It is used to treat Babesia infection (babesiosis) dogs, horses, and cattle.12 Because the drug causes frequent allergic reactions, it is usually combined with an antihistamine.3

References

References

  1. Merck Index, 11th Edition, 7165
  2. Randall JB, Laws SG (May 1947). "Phenamidine in the treatment of Babesia bigemina infections of cattle". Annals of Tropical Medicine and Parasitology. 41 (1): 39–42. doi:10.1080/00034983.1947.11685310. PMID 20249289.
  3. Benchchem