Article · Wikipedia archive · Last revised Jul 18, 2026

Orphan virus

An orphan virus is a virus that is not associated with a disease but may possess pathogenicity.

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An orphan virus is a virus that is not associated with a disease but may possess pathogenicity.1

Gilbert Dalldorf, a pathologist who showed that Coxsackie viruses paralyze mice but not humans, indicated that the term ‘orphan’ was created "in a moment of conviviality" by a group of virologists.2

Many enteroviruses are referred to as ECHO, enteric cytopathic human orphan viruses, because they were originally not associated with any disease.1

See also

See also

References

References

  1. Li L, Delwart E. From orphan virus to pathogen: the path to the clinical lab. Current Opin Virol. 2011 Oct;1(4):282-8. doi: 10.1016/j.coviro.2011.07.006.
  2. Mortimer, Philip P. "Orphan Viruses, Orphan Diseases: Still the Raw Material for Virus Discovery." Reviews in Medical Virology 23.6 (2013): 337-39. Web.