Article · Wikipedia archive · Last revised Aug 3, 2026

Nothofagin

Nothofagin is a dihydrochalcone. It is a C-linked phloretin glucoside found in rooibos and New Zealand red beech. It is a phenolic antioxidant.

Last revised
Aug 3, 2026
Read time
≈ 1 min
Length
164 w
Citations
2
Source
Wikipedia ↗
Nothofagin
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Names
IUPAC name
2',4,4',6'-Tetrahydroxy-3-C-β-D-glucopyranosyldihydrochalcone
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
  • InChI=1S/C21H24O10/c22-8-14-17(27)19(29)20(30)21(31-14)16-13(26)7-12(25)15(18(16)28)11(24)6-3-9-1-4-10(23)5-2-9/h1-2,4-5,7,14,17,19-23,25-30H,3,6,8H2/t14-,17-,19+,20-,21+/m1/s1 X markN
    Key: VZBPTZZTCBNBOZ-VJXVFPJBSA-N X markN
  • InChI=1/C21H24O10/c22-8-14-17(27)19(29)20(30)21(31-14)16-13(26)7-12(25)15(18(16)28)11(24)6-3-9-1-4-10(23)5-2-9/h1-2,4-5,7,14,17,19-23,25-30H,3,6,8H2/t14-,17-,19+,20-,21+/m1/s1
    Key: VZBPTZZTCBNBOZ-VJXVFPJBBW
  • O[C@H]1[C@H](O)[C@@H](O)[C@@H](O[C@@H]1CO)c3c(O)cc(O)c(C(=O)CCc2ccc(O)cc2)c3O
Properties
C21H24O10
Molar mass 436.413 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Nothofagin is a dihydrochalcone. It is a C-linked phloretin glucoside found in rooibos (Aspalathus linearis)1 and New Zealand red beech (Nothofagus fusca).2 It is a phenolic antioxidant.

References

References

  1. Bramati L, et al. (2002). "Quantitative Characterization of Flavonoid Compounds in Rooibos Tea (Aspalathus Linearis) by LC-UV/DAD". Journal of Agricultural and Food Chemistry. 50 (20). Elsevier: 5513–5519. doi:10.1021/jf025697h. PMID 12236672.
  2. Hillis W, Inoue T (1967). "The polyphenols of Nothofagus species - II. The heartwood of Nothofagus fusca". Phytochemistry. 6 (1): 59–67. Bibcode:1967PChem...6...59H. doi:10.1016/0031-9422(67)85008-8.
External links