Morphinone

Morphinone
	Structural formula source ↗
	Space-filling model source ↗
Names
	IUPAC name (5α)-3-Hydroxy-17-methyl-7,8-didehydro-4,5-epoxy-morphinan-6-one
Identifiers
CAS Number	467-02-7 N;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:16315 Y;
ChEMBL	ChEMBL255467 Y;
ChemSpider	4573586 Y;
ECHA InfoCard	100.006.714
KEGG	C01735 Y;
PubChem CID	5459823;
UNII	28MBK63MAW Y;
CompTox Dashboard (EPA)	DTXSID50196907 ;
	InChI InChI=1S/C17H17NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,16,19H,6-8H2,1H3/t10-,11+,16-,17-/m0/s1 Y Key: PFBSOANQDDTNGJ-YNHQPCIGSA-N Y; InChI=1/C17H17NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,16,19H,6-8H2,1H3/t10-,11+,16-,17-/m0/s1 Key: PFBSOANQDDTNGJ-YNHQPCIGBO;
	SMILES O=C1\C=C/[C@H]5[C@@H]4N(CC[C@@]52c3c(O[C@@H]12)c(O)ccc3C4)C;
Properties
Chemical formula	C17H17NO3
Molar mass	283.327 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

Morphinone is an opioid that is the intermediate when morphine is being converted to hydromorphone (trade name Dilaudid).¹

Chemical structure

Morphinone can be described as the ketone of morphine.

Legal status

Morphinone itself is an active opioid, though its potency is closer to codeine than morphine. It is, however, an important precursor and would fall under the purview of the Controlled Substances Act within the United States. Its legal status in other countries varies.

References

Hung-Wen (Ben) Liu and Tadhg P. Begley, ed. (2020). Comprehensive Natural Products III. Elsevier. ISBN 978-0-08-102691-5.

[1] Hung-Wen (Ben) Liu and Tadhg P. Begley, ed. (2020). Comprehensive Natural Products III. Elsevier. ISBN 978-0-08-102691-5.

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