| Microvascular occlusion | |
|---|---|
| Specialty | Dermatology |
Microvascular occlusion refers to conditions that can present with retiform purpura.1 It has been suggested that phenylephrine may be a cause.2
Signs and symptoms
Microvascular occlusions appears as bland necrosis without inflammation and retiform purpura.3
Causes
Microvascular occlusions can be caused by heparin-induced thrombocytopenia, cryoglobulinemia, angioinvasive organisms, embolization, disseminated intravascular coagulation, livedoid vasculopathy, cell occlusion syndromes, and iatrogenic causes.3
Outlook
The outcomes of microvascular occlusions are usually influenced by the degree, length, nature of the underlying cause, and prompt and effective treatment.3
References
References
- Jean L. Bolognia; Joseph L. Jorizzo; Ronald P. Rapini (27 August 2003). Dermatology. Elsevier Health Sciences. pp. 390–. ISBN 978-0-323-02578-2. Retrieved 20 May 2011.
- Kalajian, AH.; Turpen, KB.; Donovan, KO.; Malone, JC.; Callen, JP. (Oct 2007). "Phenylephrine-induced microvascular occlusion syndrome in a patient with a heterozygous factor V Leiden mutation". Arch Dermatol. 143 (10): 1314–7. doi:10.1001/archderm.143.10.1314. PMID 17938347.
- Dehghani, Shakiba; Abtahi-Naeini, Bahareh (2021). "COVID-19: A new cause of cutaneous microvascular occlusion syndrome". Journal of Research in Medical Sciences. 26 (1). Medknow: 119. doi:10.4103/jrms.jrms_560_21. ISSN 1735-1995. PMC 8765522.
Further reading
Further reading
- Hosseini, Nastaran-Sadat; Babaei, Sharareh; Rahimi, Hamid; Gheissari, Alaleh; Sedaghat, Banafsheh; Pourmahdi-Boroujeni, Mahsa; Abtahi-Naeini, Bahareh (2023-08-22). "Cutaneous microvascular occlusion syndrome as the first manifestation of catastrophic lupus-associated antiphospholipid antibody syndrome: a case report". Journal of Medical Case Reports. 17 (1). doi:10.1186/s13256-023-04068-9. ISSN 1752-1947. PMC 10464427. PMID 37605287.
- Ko, Christine J.; Gehlhausen, Jeff R.; McNiff, Jennifer M. (2021). "Leukocytoclastic Vasculitis and Microvascular Occlusion". Surgical Pathology Clinics. 14 (2). Elsevier BV: 309–325. doi:10.1016/j.path.2021.01.006. ISSN 1875-9181.