Article · Wikipedia archive · Last revised Jul 11, 2026

MEDA

MEDA, also known as 3-methoxy-4,5-ethylenedioxyamphetamine or as 5-methoxy-EDA, is a chemical compound of the phenethylamine, amphetamine, and EDxx families. It is the EDxx analogue of the MDxx psychedelic and entactogen MMDA (5-methoxy-MDA). In his book PiHKAL, Alexander Shulgin lists MEDA's dose as greater than 200 mg orally and its duration as unknown. MEDA produced few to no effects at tested doses. The chemical synthesis of MEDA has been described. MEDA was first described in the scientific literature by Shulgin in 1964. Subsequently, it was described in greater detail by Shulgin in PiHKAL in 1991.

Last revised
Jul 11, 2026
Read time
≈ 1 min
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Citations
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Source
Wikipedia ↗
MEDA
Clinical data
Other names3-Methoxy-4,5-ethylenedioxyamphetamine; 5-Methoxy-3,4-ethylenedioxyamphetamine; 5-Methoxy-EDA; 5-MeO-EDA
Routes of
administration		Oral1
ATC code
  • None
Pharmacokinetic data
Duration of actionUnknown1
Identifiers
  • 1-(8-methoxy-2,3-dihydro-1,4-benzodioxin-6-yl)propan-2-amine
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
Chemical and physical data
FormulaC12H17NO3
Molar mass223.272 g·mol−1
3D model (JSmol)
  • NC(CC1=CC2=C(OCCO2)C(OC)=C1)C
  • InChI=1S/C12H17NO3/c1-8(13)5-9-6-10(14-2)12-11(7-9)15-3-4-16-12/h6-8H,3-5,13H2,1-2H3 ☒N
  • Key:NRVFDGZJTPCULU-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

MEDA, also known as 3-methoxy-4,5-ethylenedioxyamphetamine or as 5-methoxy-EDA, is a chemical compound of the phenethylamine, amphetamine, and EDxx families.12 It is the EDxx analogue of the MDxx psychedelic and entactogen MMDA (5-methoxy-MDA).123 In his book PiHKAL (Phenethylamines I Have Known and Loved), Alexander Shulgin lists MEDA's dose as greater than 200 mg orally and its duration as unknown.12 MEDA produced few to no effects at tested doses.12 The chemical synthesis of MEDA has been described.1 MEDA was first described in the scientific literature by Shulgin in 1964.3 Subsequently, it was described in greater detail by Shulgin in PiHKAL in 1991.1

See also

See also

References

References

  1. Shulgin, Alexander; Shulgin, Ann (September 1991). PiHKAL: A Chemical Love Story. Berkeley, California: Transform Press. ISBN 0-9630096-0-5. OCLC 25627628. MEDA entry
  2. Shulgin AT (2003). "Basic Pharmacology and Effects". In Laing RR (ed.). Hallucinogens: A Forensic Drug Handbook. Forensic Drug Handbook Series. Elsevier Science. pp. 67–137. ISBN 978-0-12-433951-4. Archived from the original on 13 July 2025.
  3. Shulgin AT (March 1964). "3-Methoxy-4,5-methylenedioxy Amphetamine, a New Psychotomimetic Agent". Nature. 201 (4924): 1120–1121. Bibcode:1964Natur.201.1120S. doi:10.1038/2011120a0. PMID 14152788. Archived from the original on 2025-07-12.
External links