MARC2

MTARC2
Identifiers
Aliases	MTARC2, MOSC2, mitochondrial amidoxime reducing component 2, MARC2
External IDs	OMIM: 614127; MGI: 1914497; HomoloGene: 9904; GeneCards: MTARC2; OMA:MTARC2 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	220,784,815 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	184,578,648 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; left lobe of thyroid gland; ; right lobe of thyroid gland; ; right lung; ; kidney tubule; ; duodenum; ; parotid gland; ; body of pancreas; ; jejunal mucosa; ; human kidney;
	Top expressed in
	duodenum; ; left lobe of liver; ; jejunum; ; right kidney; ; parotid gland; ; lacrimal gland; ; gallbladder; ; proximal tubule; ; human kidney; ; submandibular gland;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	molybdopterin cofactor binding; molybdenum ion binding; oxidoreductase activity; pyridoxal phosphate binding; nitrate reductase activity; catalytic activity;
Cellular component	peroxisome; mitochondrion; membrane; mitochondrial outer membrane;
Biological process	detoxification of nitrogen compound; nitrate metabolic process; xenobiotic metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	54996
	67247
	ENSG00000117791
	ENSMUSG00000073481
	Q969Z3
	Q922Q1
	NM_017898; NM_001317338; NM_001331042
	NM_133684; NM_001368285; NM_001368286
	NP_001304267; NP_001317971; NP_060368
	NP_598445; NP_001355214; NP_001355215
	Wikidata
View/Edit Human	View/Edit Mouse

MOSC domain-containing protein 2, mitochondrial is a protein that in humans is encoded by the MOSC2 gene.⁵⁶

References

GRCh38: Ensembl release 89: ENSG00000117791 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000073481 – Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Anantharaman V, Aravind L (Mar 2002). "MOSC domains: ancient, predicted sulfur-carrier domains, present in diverse metal-sulfur cluster biosynthesis proteins including Molybdenum cofactor sulfurases". FEMS Microbiol Lett. 207 (1): 55–61. doi:10.1016/S0378-1097(01)00515-8. PMID 11886751.
"Entrez Gene: MOSC2 MOCO sulphurase C-terminal domain containing 2".

Further reading

Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
Havemeyer A, Bittner F, Wollers S, et al. (2007). "Identification of the missing component in the mitochondrial benzamidoxime prodrug-converting system as a novel molybdenum enzyme". J. Biol. Chem. 281 (46): 34796–802. doi:10.1074/jbc.M607697200. PMID 16973608.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000117791 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000073481 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11886751-5] Anantharaman V, Aravind L (Mar 2002). "MOSC domains: ancient, predicted sulfur-carrier domains, present in diverse metal-sulfur cluster biosynthesis proteins including Molybdenum cofactor sulfurases". FEMS Microbiol Lett. 207 (1): 55–61. doi:10.1016/S0378-1097(01)00515-8. PMID 11886751.

[entrez-6] "Entrez Gene: MOSC2 MOCO sulphurase C-terminal domain containing 2".

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