LRIT3

LRIT3
Identifiers
Aliases	LRIT3, CSNB1F, FIGLER4, leucine-rich repeat, Ig-like and transmembrane domains 3, leucine rich repeat, Ig-like and transmembrane domains 3
External IDs	OMIM: 615004; MGI: 2685267; HomoloGene: 19426; GeneCards: LRIT3; OMA:LRIT3 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	109,872,315 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	129,597,679 bp
RNA expression pattern
	Top expressed in
	testicle; ; superior frontal gyrus; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; primary visual cortex; ; Brodmann area 9; ; renal cortex; ; tibial nerve; ; granulocyte; ; right frontal lobe;
	Top expressed in
	neural layer of retina; ; embryo; ; secondary oocyte; ; primary oocyte; ; zygote; ; embryo; ; lens; ; renal cortex; ; proximal tubule; ; human kidney;
	More reference expression data
	n/a
Orthologs
	345193
	242235
	ENSG00000183423
	ENSMUSG00000093865
	Q3SXY7
	W8DXL4
	NM_198506
	NM_001205102; NM_001287224
	NP_940908
	NP_001274153
	Wikidata
View/Edit Human	View/Edit Mouse

Leucine-rich repeat, immunoglobulin-like and transmembrane domains 3 is a protein that in humans is encoded by the LRIT3 gene.⁵

References

Further reading

Kalsi G, Kuo PH, Aliev F, Alexander J, McMichael O, Patterson DG, Walsh D, Zhao Z, Schuckit M, Nurnberger J, Edenberg H, Kramer J, Hesselbrock V, Tischfield JA, Vladimirov V, Prescott CA, Dick DM, Kendler KS, Riley BP (June 2010). "A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts". Human Molecular Genetics. 19 (12): 2497–506. doi:10.1093/hmg/ddq112. PMC 2876884. PMID 20332099.
Kim SD, Liu JL, Roscioli T, Buckley MF, Yagnik G, Boyadjiev SA, Kim J (May 2012). "Leucine-rich repeat, immunoglobulin-like and transmembrane domain 3 (LRIT3) is a modulator of FGFR1". FEBS Letters. 586 (10): 1516–21. doi:10.1016/j.febslet.2012.04.010. PMC 3372856. PMID 22673519.
Zeitz C, Jacobson SG, Hamel CP, Bujakowska K, Neuillé M, Orhan E, Zanlonghi X, Lancelot ME, Michiels C, Schwartz SB, Bocquet B, Antonio A, Audier C, Letexier M, Saraiva JP, Luu TD, Sennlaub F, Nguyen H, Poch O, Dollfus H, Lecompte O, Kohl S, Sahel JA, Bhattacharya SS, Audo I (January 2013). "Whole-exome sequencing identifies LRIT3 mutations as a cause of autosomal-recessive complete congenital stationary night blindness". American Journal of Human Genetics. 92 (1): 67–75. doi:10.1016/j.ajhg.2012.10.023. PMC 3542465. PMID 23246293.