KCNA6

KCNA6
Identifiers
Aliases	KCNA6, HBK2, KV1.6, PPP1R96, potassium voltage-gated channel subfamily A member 6
External IDs	OMIM: 176257; MGI: 96663; HomoloGene: 1684; GeneCards: KCNA6; OMA:KCNA6 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	4,813,318 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	126,717,637 bp
RNA expression pattern
	Top expressed in
	testicle; ; prefrontal cortex; ; islet of Langerhans; ; ventricular zone; ; Brodmann area 9; ; Achilles tendon; ; cingulate gyrus; ; right frontal lobe; ; anterior cingulate cortex; ; ganglionic eminence;
	Top expressed in
	dentate gyrus of hippocampal formation granule cell; ; lumbar spinal ganglion; ; medial dorsal nucleus; ; superior frontal gyrus; ; lateral hypothalamus; ; globus pallidus; ; primary visual cortex; ; medial vestibular nucleus; ; trigeminal ganglion; ; cerebellar cortex;
	More reference expression data
	n/a
Gene ontology
Molecular function	voltage-gated potassium channel activity; ion channel activity; potassium channel activity; delayed rectifier potassium channel activity; voltage-gated ion channel activity;
Cellular component	axon terminus; integral component of membrane; voltage-gated potassium channel complex; axon; plasma membrane; potassium channel complex; integral component of plasma membrane; membrane;
Biological process	potassium ion transport; regulation of ion transmembrane transport; protein homooligomerization; ion transport; transmembrane transport; potassium ion transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	3742
	16494
	ENSG00000151079
	ENSMUSG00000038077
	P17658
	Q61923
	NM_002235
	NM_013568
	NP_002226
	NP_038596
	Wikidata
View/Edit Human	View/Edit Mouse

Potassium voltage-gated channel subfamily A member 6 also known as K_v1.6 is a protein that in humans is encoded by the KCNA6 gene.⁵ The protein encoded by this gene is a voltage-gated potassium channel subunit.

References

GRCh38: Ensembl release 89: ENSG00000151079 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000038077 – Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels" (PDF). Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104. S2CID 219195192. Archived from the original (PDF) on 2018-05-24. Retrieved 2018-05-23.

External links

Kv1.6+Potassium+Channel at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
KCNA6+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000151079 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000038077 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid16382104-5] Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels" (PDF). Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104. S2CID 219195192. Archived from the original (PDF) on 2018-05-24. Retrieved 2018-05-23.

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Further reading

External links