Article · Wikipedia archive · Last revised Jul 19, 2026

Jan Wolff

Jan Wolff is a German medical doctor who, together with Israel Lyon Chaikoff, discovered the Wolff–Chaikoff effect, a compensatory mechanism preventing thyrotoxicosis in oversupply with iodine.

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Jul 19, 2026
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Jan Wolff is a German medical doctor who, together with Israel Lyon Chaikoff, discovered the Wolff–Chaikoff effect, a compensatory mechanism preventing thyrotoxicosis in oversupply with iodine.1

Wolff was born in Germany, and after his father was barred from practicing medicine there, moved with his parents to the Netherlands, then to England, then to San Francisco, California.2 He is a graduate of University of California, Berkeley.2

References

References

  1. Wolff J, Chaikoff IL (1948). "Plasma inorganic iodide as a homeostatic regulator of thyroid function". J Biol Chem. 174 (2): 555–564. doi:10.1016/S0021-9258(18)57335-X. PMID 18865621.
  2. Wolff, Jan; Kaplan, Michael M.; Schneider, Arthur B. "Jan Wolff Reflects on His Career as He Approaches His 99th Birthday". Clinical Thyroidology. 35 (10): 395–397. doi:10.1089/ct.2023;35.395-397.