Immunoscintigraphy

Immunoscintigraphy
Immunoscintigraphy
Purpose	detect cancer cells

Immunoscintigraphy is a nuclear medicine procedure used to find cancer cells in the body by injecting a radioactively labeled antibody, which binds predominantly to cancer cells and then scanning for concentrations of radioactive emissions.¹²

Clinical applications

Immunoscintigraphy is performed using a variety of radiopharmaceuticals, for a large range of purposes. Colorectal cancer is one of the most studied areas, with indium-111 or technetium-99m labelled epitopes of the carcinoembryonic antigen.³ The antibody capromab pendetide reacts with prostate membrane specific antigen (PMSA) and can be labelled with ¹¹¹In.⁴

References

"Imaging Techniques for the Diagnosis of Ovarian Cancers: Immunoscintigraphy". 21 December 2004.
"Immunoscintigraphy". NCI Dictionary of Cancer Terms. National Cancer Institute. Retrieved 1 June 2017.
Matzku, Siegfried; Stahel, Rolf A (1999). Antibodies in Diagnosis and Therapy. CRC Press. p. 143. ISBN 9789057023101.
Fass, Leonard (August 2008). "Imaging and cancer: A review". Molecular Oncology. 2 (2): 115–152. doi:10.1016/j.molonc.2008.04.001. PMC 5527766. PMID 19383333.

[1] "Imaging Techniques for the Diagnosis of Ovarian Cancers: Immunoscintigraphy". 21 December 2004.

[2] "Immunoscintigraphy". NCI Dictionary of Cancer Terms. National Cancer Institute. Retrieved 1 June 2017.

[3] Matzku, Siegfried; Stahel, Rolf A (1999). Antibodies in Diagnosis and Therapy. CRC Press. p. 143. ISBN 9789057023101.

[4] Fass, Leonard (August 2008). "Imaging and cancer: A review". Molecular Oncology. 2 (2): 115–152. doi:10.1016/j.molonc.2008.04.001. PMC 5527766. PMID 19383333.

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Clinical applications

See also

References