IL17RC

IL17RC
Identifiers
Aliases	IL17RC, IL17-RL, IL17RL, CANDF9, interleukin 17 receptor C
External IDs	OMIM: 610925; MGI: 2159336; HomoloGene: 15894; GeneCards: IL17RC; OMA:IL17RC - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	9,933,630 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	113,460,101 bp
RNA expression pattern
	Top expressed in
	anterior pituitary; ; right adrenal cortex; ; right lobe of liver; ; gastric mucosa; ; left adrenal cortex; ; skin of abdomen; ; skin of leg; ; muscle layer of sigmoid colon; ; apex of heart; ; right lobe of thyroid gland;
	Top expressed in
	ileum; ; jejunum; ; lip; ; esophagus; ; colon; ; zone of skin; ; urinary bladder; ; white adipose tissue; ; duodenum; ; humerus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	interleukin-17 receptor activity; signaling receptor binding;
Cellular component	integral component of membrane; cell surface; integral component of plasma membrane; membrane; plasma membrane;
Biological process	positive regulation of cytokine production involved in inflammatory response; granulocyte chemotaxis; defense response to fungus; interleukin-17-mediated signaling pathway; cytokine-mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	84818
	171095
	ENSG00000163702
	ENSMUSG00000030281
	Q8NAC3
	Q8K4C2
NM_001203263; NM_001203264; NM_001203265; NM_032732; NM_153460;
	NM_153461; NM_153462; NM_153463; NM_001367278; NM_001367279; NM_001367280
	NM_134159; NM_178942
NP_001190192; NP_001190193; NP_001190194; NP_116121; NP_703190;
	NP_703191; NP_001354207; NP_001354208; NP_001354209
	NP_598920; NP_849273
	Wikidata
View/Edit Human	View/Edit Mouse

Interleukin-17 receptor C is a protein that in humans is encoded by the IL17RC gene.⁵⁶

Function

This gene encodes a single-pass transmembrane protein that shares limited similarity with the interleukin-17 receptor. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, but the full-length nature of only three have been determined to date.⁶

References

GRCh38: Ensembl release 89: ENSG00000163702 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000030281 – Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Haudenschild D, Moseley T, Rose L, Reddi AH (February 2002). "Soluble and transmembrane isoforms of novel interleukin-17 receptor-like protein by RNA splicing and expression in prostate cancer". The Journal of Biological Chemistry. 277 (6): 4309–16. doi:10.1074/jbc.M109372200. PMID 11706037.
"Entrez Gene: IL17RC interleukin 17 receptor C".

External links

IL17RC+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000163702 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000030281 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11706037-5] Haudenschild D, Moseley T, Rose L, Reddi AH (February 2002). "Soluble and transmembrane isoforms of novel interleukin-17 receptor-like protein by RNA splicing and expression in prostate cancer". The Journal of Biological Chemistry. 277 (6): 4309–16. doi:10.1074/jbc.M109372200. PMID 11706037.

[entrez-6] "Entrez Gene: IL17RC interleukin 17 receptor C".

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IL17RC

Function

See also

References

Further reading

External links