Article · Wikipedia archive · Last revised Jul 31, 2026

Hydroxymetronidazole

Hydroxymetronidazole is the main metabolite of metronidazole. Both have antibiotic and antiprotozoal activity.

Last revised
Jul 31, 2026
Read time
≈ 1 min
Length
109 w
Citations
1
Source
Hydroxymetronidazole
source ↗
Names
Preferred IUPAC name
2-[2-(Hydroxymethyl)-5-nitro-1H-imidazol-1-yl]ethan-1-ol
Other names
Metronidazole-OH; 1-(2-Hydroxyethyl)-2-hydroxymethyl-5-nitroimidazole
Identifiers
3D model (JSmol)
Abbreviations MNZOH
ChemSpider
ECHA InfoCard 100.169.434
UNII
  • InChI=1S/C6H9N3O4/c10-2-1-8-5(4-11)7-3-6(8)9(12)13/h3,10-11H,1-2,4H2 X markN
    Key: AEHPOYAOLCAMIU-UHFFFAOYSA-N X markN
  • InChI=1/C6H9N3O4/c10-2-1-8-5(4-11)7-3-6(8)9(12)13/h3,10-11H,1-2,4H2
    Key: AEHPOYAOLCAMIU-UHFFFAOYAK
  • C1=C(N(C(=N1)CO)CCO)[N+](=O)[O-]
Properties
C6H9N3O4
Molar mass 187.15 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Hydroxymetronidazole is the main metabolite of metronidazole. Both have antibiotic and antiprotozoal activity.1

References

References

  1. Haberfeld H, ed. (2020). Austria-Codex (in German). Vienna: Österreichischer Apothekerverlag. Anaerobex-Filmtabletten.