HSPA14

HSPA14
Identifiers
Aliases	HSPA14, HSP70-4, HSP70L1, heat shock protein family A (Hsp70) member 14
External IDs	OMIM: 610369; MGI: 1354164; HomoloGene: 74307; GeneCards: HSPA14; OMA:HSPA14 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	14,871,741 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	3,513,851 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; middle temporal gyrus; ; right testis; ; rectum; ; deltoid muscle; ; left testis; ; gastrocnemius muscle; ; mucosa of sigmoid colon; ; vastus lateralis muscle; ; Skeletal muscle tissue of biceps brachii;
	Top expressed in
	primitive streak; ; epiblast; ; otic placode; ; abdominal wall; ; otic vesicle; ; yolk sac; ; dermis; ; morula; ; morula; ; embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; protein binding; ATP binding; ATPase activity; heat shock protein binding; protein folding chaperone activity; unfolded protein binding; misfolded protein binding;
Cellular component	cytoplasm; cytosol; ribosome; membrane; polysome;
Biological process	'de novo' cotranslational protein folding; cytoplasmic translation; regulation of translational fidelity; response to unfolded protein; cellular response to heat; Unfolded Protein Response; protein refolding; chaperone cofactor-dependent protein refolding;
	Sources:Amigo / QuickGO
Orthologs
	51182
	50497
	ENSG00000187522
	ENSMUSG00000109865
	Q0VDF9; Q8TAQ0
	Q99M31
	NM_001037538; NM_001278205; NM_016299
	NM_001037542; NM_015765; NM_001355397
	NP_057383; NP_001265134.1
	NP_056580; NP_001342326
	Wikidata
View/Edit Human	View/Edit Mouse

Heat shock 70 kDa protein 14 also known as HSP70-like protein 1 or heat shock protein HSP60 is a protein that in humans is encoded by the HSPA14 gene.⁵⁶

References

GRCh38: Ensembl release 89: ENSG00000187522 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000109865 – Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Wan T, Zhou X, Chen G, An H, Chen T, Zhang W, Liu S, Jiang Y, Yang F, Wu Y, Cao X (March 2004). "Novel heat shock protein Hsp70L1 activates dendritic cells and acts as a Th1 polarizing adjuvant". Blood. 103 (5): 1747–54. doi:10.1182/blood-2003-08-2828. PMID 14592822.
"Entrez Gene: HSPA14 heat shock 70kDa protein 14".

External links

HSPA14+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000187522 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000109865 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid14592822-5] Wan T, Zhou X, Chen G, An H, Chen T, Zhang W, Liu S, Jiang Y, Yang F, Wu Y, Cao X (March 2004). "Novel heat shock protein Hsp70L1 activates dendritic cells and acts as a Th1 polarizing adjuvant". Blood. 103 (5): 1747–54. doi:10.1182/blood-2003-08-2828. PMID 14592822.

[entrez-6] "Entrez Gene: HSPA14 heat shock 70kDa protein 14".

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References

Further reading

External links