Groundsel is a common name for several plants and may refer to:
- Members of the genus Senecio
- Creeping groundsel, Senecio angulatus
- Common groundsel, Senecio vulgaris
- Welsh groundsel, Senecio cambrensis
- York radiate groundsel, Senecio eboracensis
- Eastern groundsel, Senecio vernalis
- Heath groundsel, Senecio sylvaticus
- Sticky groundsel, Senecio viscosus
- Groundsel bush, Baccharis halimifolia
- Orange-flowered groundsel, Pseudogynoxys chenopodioides
- Members of Dendrosenecio, the giant groundsels
- Members of Packera, a segregate of Senecio
- Golden groundsel, Packera aurea (Senecio aureus)
- Golden groundsel, Packera obovata (Senecio obovatus)
- Members of Roldana, a segregate of Senecio
- Members of Tephroseris1