GPR62

GPR62
Identifiers
Aliases	GPR62, GPCR8, KPG_005, G protein-coupled receptor 62
External IDs	OMIM: 606917; MGI: 3525078; HomoloGene: 50962; GeneCards: GPR62; OMA:GPR62 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	51,957,499 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	106,343,137 bp
RNA expression pattern
	Top expressed in
	inferior ganglion of vagus nerve; ; C1 segment; ; internal globus pallidus; ; subthalamic nucleus; ; endothelial cell; ; ventral tegmental area; ; corpus callosum; ; substantia nigra; ; external globus pallidus; ; medulla oblongata;
	Top expressed in
	lumbar subsegment of spinal cord; ; seminiferous tubule; ; deep cerebellar nuclei; ; substantia nigra; ; anterior horn of spinal cord; ; suprachiasmatic nucleus; ; pontine nuclei; ; lateral geniculate nucleus; ; spermatocyte; ; ventral tegmental area;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity; protein binding; identical protein binding; arrestin family protein binding;
Cellular component	integral component of membrane; receptor complex; membrane; plasma membrane; endosome; endosome membrane;
Biological process	signal transduction; G protein-coupled receptor signaling pathway; positive regulation of cAMP-mediated signaling; inositol phosphate-mediated signaling;
	Sources:Amigo / QuickGO
Orthologs
	118442
	436090
	ENSG00000180929
	ENSMUSG00000091735
	Q9BZJ7
	Q80UC6
	NM_080865
	NM_001159652
	NP_543141
	NP_001153124
	Wikidata
View/Edit Human	View/Edit Mouse

Probable G-protein coupled receptor 62 is a protein that in humans is encoded by the GPR62 gene.⁵⁶

G protein–coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM]⁶

References

GRCh38: Ensembl release 89: ENSG00000180929 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000091735 – Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Lee DK, George SR, Cheng R, Nguyen T, Liu Y, Brown M, Lynch KR, O'Dowd BF (Feb 2001). "Identification of four novel human G protein-coupled receptors expressed in the brain". Brain Res Mol Brain Res. 86 (1–2): 13–22. doi:10.1016/S0169-328X(00)00242-4. PMID 11165367.
"Entrez Gene: GPR62 G protein-coupled receptor 62".

References

Further reading