Article · Wikipedia archive · Last revised Jun 13, 2026

Germacranolide

Germacranolides are a group of natural chemical compounds classified as sesquiterpene lactones. They are found in a variety of plant species and are known for their diverse and complex topology, as well as a wide array of pharmacological activities.

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Jun 13, 2026
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Chemical structure of costunolide, a prototypical germacranolide source ↗

Germacranolides are a group of natural chemical compounds classified as sesquiterpene lactones. They are found in a variety of plant species1 and are known for their diverse and complex topology, as well as a wide array of pharmacological activities.2

References

References

  1. Fraga, B. M. (1988). "Natural sesquiterpenoids" (PDF). Natural Product Reports. 5 (5): 497–521. doi:10.1039/np9880500497.
  2. Patouret, Rémi; Cham, Ning; Chiba, Shunsuke (2024-05-06). "Collective Synthesis of Highly Oxygenated (Furano)germacranolides Derived from Elephantopus mollis and Elephantopus tomentosus". Angewandte Chemie International Edition in English. 63 (19) e202402050. doi:10.1002/anie.202402050. ISSN 1521-3773. PMID 38488804.