Franssen is a Dutch patronymic surname meaning "son of Frans". It can refer to:
- Everhardt Franßen (born 1937), German judge
- Jan Franssen (born 1951), Dutch politician
- Jo Franssen (1909–1995), Dutch politician
- MHH Franssen (1903–1981), Dutch lawyer
- Margot Franssen (born 1952), Dutch-born Canadian philanthropist, activist and entrepreneur
- Nico Valentinus Franssen (1932–1993), Dutch-born American physicist and inventor
- Franssen effect, an auditory illusion discovered by him
Franssens
- Joep Franssens (born 1955), Dutch composer