Article · Wikipedia archive · Last revised Jun 28, 2026

Fluoroacetamide

Fluoroacetamide is an organic compound with the chemical formula FCH2CONH2. It is a compound based on acetamide with one fluorine atom replacing hydrogen on the methyl group. It is a very toxic metabolic poison which disrupts the citric acid cycle and was used as a rodenticide. If consumed it can cause reproductive disorders. In addition it causes serious eye damage.

Last revised
Jun 28, 2026
Read time
≈ 1 min
Length
294 w
Citations
3
Source
Wikipedia ↗
Fluoroacetamide
Skeletal formula of fluoroacetamide
Skeletal formula of fluoroacetamide source ↗
Ball-and-stick model of fluoroacetamide
Ball-and-stick model of fluoroacetamide source ↗
Names
IUPAC name
2-Fluoroacetamide
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.010.331
KEGG
UNII
  • InChI=1S/C2H4FNO/c3-1-2(4)5/h1H2,(H2,4,5) checkY
    Key: FVTWJXMFYOXOKK-UHFFFAOYSA-N checkY
  • InChI=1/C2H4FNO/c3-1-2(4)5/h1H2,(H2,4,5)
    Key: FVTWJXMFYOXOKK-UHFFFAOYAA
  • C(C(=O)N)F
  • FCC(=O)N
Properties
FCH2CONH2
Molar mass 77.058 g·mol−1
Appearance Colorless crystals
Melting point 107 to 109 °C (225 to 228 °F; 380 to 382 K)
Soluble
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
 Very toxic
GHS labelling:
GHS06: Toxic
Danger
H300+H310
P262, P264, P270, P280, P301+P310+P330, P302, P350, P362, P405, P501
NFPA 704 (fire diamond)
NFPA 704 four-colored diamondHealth 4: Very short exposure could cause death or major residual injury. E.g. VX gasFlammability 1: Must be pre-heated before ignition can occur. Flash point over 93 °C (200 °F). E.g. canola oilInstability (yellow): no hazard codeSpecial hazards (white): no code
source ↗
4
1
Lethal dose or concentration (LD, LC):
80 mg/kg (dermal, rat)
550 mg/m3(mouse, inhalation, dust/mist)
Safety data sheet (SDS) 1
Related compounds
Related compounds
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Fluoroacetamide is an organic compound with the chemical formula FCH2CONH2. It is a compound based on acetamide with one fluorine atom replacing hydrogen on the methyl group. It is a very toxic metabolic poison which disrupts the citric acid cycle and was used as a rodenticide.2 If consumed it can cause reproductive disorders. In addition it causes serious eye damage.1

See also

See also

References

References

  1. "SAFETY DATA SHEET". Sigma Aldrich. Retrieved November 27, 2025.
  2. Matsumura, F; O'Brien, RD (Oct 1963). "A COMPARATIVE STUDY OF THE MODES OF ACTION OF FLUOROACETAMIDE AND FLUOROACETATE IN THE MOUSE AND AMERICAN COCKROACH". Biochem Pharmacol. 12: 1201–5. doi:10.1016/0006-2952(63)90095-9. PMID 14074120.