Article · Wikipedia archive · Last revised Jul 31, 2026

Fletazepam

Fletazepam is a drug which is a benzodiazepine derivative. It has sedative and anxiolytic effects similar to those produced by other benzodiazepine derivatives, but is mainly notable for its strong muscle relaxant properties.

Last revised
Jul 31, 2026
Read time
≈ 1 min
Length
166 w
Citations
3
Source
Wikipedia ↗
Fletazepam
Clinical data
ATC code
  • none
Identifiers
  • 7-chloro-5-(2-fluorophenyl)-1-(2,2,2-trifluoroethyl)-2,3-dihydro-1,4-benzodiazepine
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.047.309
Chemical and physical data
FormulaC17H13ClF4N2
Molar mass356.75 g·mol−1
3D model (JSmol)
  • FC1=CC=CC=C1C2=NCCN(CC(F)(F)F)C3=C2C=C(Cl)C=C3
  • InChI=1S/C17H13ClF4N2/c18-11-5-6-15-13(9-11)16(12-3-1-2-4-14(12)19)23-7-8-24(15)10-17(20,21)22/h1-6,9H,7-8,10H2 checkY
  • Key:CIZCSUNUBQXVFP-UHFFFAOYSA-N checkY
  (verify)

Fletazepam1 is a drug which is a benzodiazepine derivative. It has sedative and anxiolytic effects similar to those produced by other benzodiazepine derivatives, but is mainly notable for its strong muscle relaxant properties.2

Fletazepam is most closely related to other N-trifluoroethyl substituted benzodiazepines such as halazepam and quazepam.3

See also

See also

References

References

  1. DE 2106175, Steinmann, Martin, "Neue 1-Polyfluoralkylbenzodiazepine und Verfahren zu ihrer Herstellung [Novel 1-polyfluoroalkylbenzodiazepines and processes for their preparation]", published 1971-09-30, assigned to Sherico Ltd. 
  2. Barnett A, Goldstein J, Fiedler EP, Taber RI (November 1974). "The pharmacology of fletazepam a centrally-acting muscle relaxant". Archives Internationales de Pharmacodynamie et de Therapie. 212 (1): 164–74. PMID 4476200.
  3. Iorio LC, Barnett A, Billard W (July 1984). "Selective affinity of 1-N-trifluoroethyl benzodiazepines for cerebellar type 1 receptor sites". Life Sciences. 35 (1): 105–13. doi:10.1016/0024-3205(84)90157-7. PMID 6738302.