Fascicle or fasciculus may refer to:
Anatomy and histology
- Muscle fascicle, a bundle of skeletal muscle fibers
- Nerve fascicle, a bundle of axons (nerve fibers)
- Fascicular pattern of histopathologic architecture
Botany
- Fascicle (botany), a cluster of flowers or leaves, such as the bundles of the thin leaves (or needles) of pines
- A discrete bundle of vascular tissue
Other uses
- Fasciculus, a fossil comb jelly
- Fasciculus Chemicus, a 17th-century anthology of alchemical writings
- Fascicle (book), a discrete section of a larger book or other published work issued in serial form