Eberconazole

Eberconazole
Clinical data
Trade names	Ebernet
Legal status
Legal status	US: Not FDA approved;
Identifiers
	IUPAC name 1-(1,3-Dichloro-6,11-dihydro-5H-dibenzo[1,2-a:1',4'-e] [7]annulen-11-yl)imidazole;
CAS Number	128326-82-9;
PubChem CID	72051;
ChemSpider	65038;
UNII	V7O1U41C9B;
CompTox Dashboard (EPA)	DTXSID90926104 ;
Chemical and physical data
Formula	C18H14Cl2N2
Molar mass	329.22 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1CC2=CC(=CC(=C2C(C3=CC=CC=C31)N4C=CN=C4)Cl)Cl;
	InChI InChI=1S/C18H14Cl2N2/c19-14-9-13-6-5-12-3-1-2-4-15(12)18(17(13)16(20)10-14)22-8-7-21-11-22/h1-4,7-11,18H,5-6H2; Key:MPTJIDOGFUQSQH-UHFFFAOYSA-N;

Eberconazole is an antifungal drug. As a 1% topical cream, it is an effective treatment for dermatophytosis, candidiasis, and pityriasis.¹²³

It was approved for use in Spain in 2015 and is sold under the trade name Ebernet.⁴ It is also approved for use in Panama, Guatemala, Costa Rica, Honduras, and the Dominican Republic.¹

References

"Ebernet". NewBridge Pharmaceuticals. Archived from the original on 2016-04-24. Retrieved 2017-01-15.
del Palacio A, Ortiz FJ, Pérez A, Pazos C, Garau M, Font E (2001). "A double-blind randomized comparative trial: eberconazole 1% cream versus clotrimazole 1% cream twice daily in Candida and dermatophyte skin infections". Mycoses. 44 (5): 173–80. doi:10.1046/j.1439-0507.2001.00632.x. PMID 11486455.
Repiso Montero T, López S, Rodríguez C, del Rio R, Badell A, Gratacós MR (May 2006). "Eberconazole 1% cream is an effective and safe alternative for dermatophytosis treatment: multicenter, randomized, double-blind, comparative trial with miconazole 2% cream". International Journal of Dermatology. 45 (5): 600–4. doi:10.1111/j.1365-4632.2006.02841.x. PMID 16700802.
"Eberconazole". Drugs.com. Archived from the original on 2021-01-17. Retrieved 2017-01-15.

[nbpharma-1] "Ebernet". NewBridge Pharmaceuticals. Archived from the original on 2016-04-24. Retrieved 2017-01-15.

[2] Palacio A, Ortiz FJ, Pérez A, Pazos C, Garau M, Font E (2001). "A double-blind randomized comparative trial: eberconazole 1% cream versus clotrimazole 1% cream twice daily in Candida and dermatophyte skin infections". Mycoses. 44 (5): 173–80. doi:10.1046/j.1439-0507.2001.00632.x. PMID 11486455.

[3] Repiso Montero T, López S, Rodríguez C, del Rio R, Badell A, Gratacós MR (May 2006). "Eberconazole 1% cream is an effective and safe alternative for dermatophytosis treatment: multicenter, randomized, double-blind, comparative trial with miconazole 2% cream". International Journal of Dermatology. 45 (5): 600–4. doi:10.1111/j.1365-4632.2006.02841.x. PMID 16700802.

[4] "Eberconazole". Drugs.com. Archived from the original on 2021-01-17. Retrieved 2017-01-15.

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