Article · Wikipedia archive · Last revised Jul 30, 2026

Divaplon

Divaplon (RU-32698) is a nonbenzodiazepine, anxiolytic and anticonvulsant drug from the imidazopyrimidine family of drugs. It acts as a partial agonist at the "benzodiazepine site" of the GABAA receptor in the brain.

Last revised
Jul 30, 2026
Read time
≈ 1 min
Length
154 w
Citations
3
Source
Wikipedia ↗
Divaplon
Clinical data
ATC code
  • none
Identifiers
  • (6-ethyl-7-methoxy-5-methylimidazo[1,2-a]pyrimidin-2-yl)-phenylmethanone
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC17H17N3O2
Molar mass295.342 g·mol−1
3D model (JSmol)
  • CCC1=C(N2C=C(N=C2N=C1OC)C(=O)C3=CC=CC=C3)C
  • InChI=1S/C17H17N3O2/c1-4-13-11(2)20-10-14(18-17(20)19-16(13)22-3)15(21)12-8-6-5-7-9-12/h5-10H,4H2,1-3H3
  • Key:NRJVHCSYLGLURI-UHFFFAOYSA-N
  (verify)

Divaplon (RU-32698) is a nonbenzodiazepine, anxiolytic and anticonvulsant drug from the imidazopyrimidine family of drugs. It acts as a partial agonist at the "benzodiazepine site" of the GABAA receptor in the brain.123

References

References

  1. Feely M, Boyland P, Picardo A, Cox A, Gent JP (May 1989). "Lack of anticonvulsant tolerance with RU 32698 and Ro 17-1812". European Journal of Pharmacology. 164 (2): 377–80. doi:10.1016/0014-2999(89)90482-2. PMID 2759183.
  2. Sanger DJ, Joly D, Perrault G (September 1995). "Benzodiazepine (omega) receptor partial agonists and the acquisition of conditioned fear in mice". Psychopharmacology. 121 (1): 104–8. doi:10.1007/BF02245596. PMID 8539334. S2CID 32627339.
  3. Pellón R, Ruíz A, Lamas E, Rodríguez C (February 2007). "Pharmacological analysis of the effects of benzodiazepines on punished schedule-induced polydipsia in rats". Behavioural Pharmacology. 18 (1): 81–7. doi:10.1097/FBP.0b013e3280143212. PMID 17218801. S2CID 40188048.