Article · Wikipedia archive · Last revised Aug 1, 2026

Desmolase

A desmolase is any of various enzymes that catalyze the formation or destruction of carbon-carbon bonds within a molecule. These enzymes play a significant role in cellular respiration and in fermentation. Desmolases are involved in steroidogenesis.

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Aug 1, 2026
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A desmolase is any of various enzymes that catalyze the formation or destruction of carbon-carbon bonds within a molecule. These enzymes play a significant role in cellular respiration and in fermentation.1 Desmolases are involved in steroidogenesis.

Examples of desmolases are:

  • Cholesterol side-chain cleavage enzyme, also called 20,22-desmolase; converts cholesterol to pregnenolone.
  • 17,20-Desmolase, also called CYP17A1 or 17α-hydroxylase; converts pregnenolone to 17α-hydroxypregnenolone, and progesterone to 17α-hydroxyprogesterone.
  • Diacetyl desmolase is added to beer late in the brewing process to remove diacetyl flavor that may have accumulated during processing.2
See also

See also

References

References

  1. Wallerstein, Leo (1939). "Enzyme Preparations from Microorganisms: Commercial Production and Industrial Application". Industrial & Engineering Chemistry. 31 (10): 1218–1224. doi:10.1021/ie50358a012.
  2. Gutcho, Marcia Halpern (1969). Alcoholic Malt Beverages, 1969. Food Processing Reviews #7. Park Ridge, New Jersey: Noyes Development Corporation. p. 221. ISBN 978-0-8155-0282-1.