Article · Wikipedia archive · Last revised Jul 4, 2026

Clomifenoxide

Clomifenoxide (INN), also known as clomifene N-oxide, is a nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group that is described as an antiestrogen and "gonad stimulant" and was never marketed. It is an active metabolite of clomifene.

Last revised
Jul 4, 2026
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≈ 1 min
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Wikipedia ↗
Clomifenoxide
Clinical data
Other namesClomifene N-oxide
Identifiers
  • (E,Z)-2-(p-(2-Chloro-1,2-diphenylvinyl)phenoxy)triethylamine N-oxide
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC26H28ClNO2
Molar mass421.97 g·mol−1
3D model (JSmol)
  • [N+](CCOc1ccc(cc1)C(=C(/c1ccccc1)Cl)\c1ccccc1)(CC)(CC)[O-]
  • InChI=1S/C26H28ClNO2/c1-3-28(29,4-2)19-20-30-24-17-15-22(16-18-24)25(21-11-7-5-8-12-21)26(27)23-13-9-6-10-14-23/h5-18H,3-4,19-20H2,1-2H3/b26-25-
  • Key:PGHWCZITRQNIPM-QPLCGJKRSA-N

Clomifenoxide (INN), also known as clomifene N-oxide, is a nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group that is described as an antiestrogen and "gonad stimulant" and was never marketed.12 It is an active metabolite of clomifene.34

See also

See also

References

References

  1. Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 298–. ISBN 978-1-4757-2085-3.
  2. Negwer M, Scharnow HG (2001). Organic-chemical drugs and their synonyms: (an international survey). Wiley-VCH. p. 3506. ISBN 978-3-527-30247-5.
  3. Analytical Profiles of Drug Substances and Excipients. Academic Press. 20 March 1998. pp. 113–. ISBN 978-0-08-086120-3.
  4. Goodwin BL (10 November 2004). Handbook of Biotransformations of Aromatic Compounds. CRC Press. pp. 3–. ISBN 978-0-203-64196-5.