Article · Wikipedia archive · Last revised Aug 11, 2026

CLaCS

CLaCS is a treatment for leg vein lesions by combining transdermal laser effect and injection sclerotherapy, all under skin cooling. The laser causes a selective photothermolysis damaging the vein wall. The vein's lumen gets smaller. On a second procedure, sclerosing agent is injected where the vein is still open. This combination can be used treat veins that could be treated by phleboectomy or foam sclerotherapy - more invasive options. To improve results, CLaCS can be guided by Augmented Reality.

Last revised
Aug 11, 2026
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CLaCS (Cryo-Laser and Cryo-Sclerotherapy) is a treatment for leg vein lesions by combining transdermal laser effect and injection sclerotherapy, all under skin cooling (Cryo - cold air blown onto the skin at -20C).123 The laser causes a selective photothermolysis damaging the vein wall. The vein's lumen gets smaller. On a second procedure, sclerosing agent is injected where the vein is still open. This combination can be used treat veins that could be treated by phleboectomy or foam sclerotherapy - more invasive options. To improve results, CLaCS can be guided by Augmented Reality4 (near-infrared vein finder).5

CLaCS was created by Dr. Roberto Kasuo Miyake (also knowns as Kasuo Miyake), in 1999, to adhere to patients' requests for treatment that did not require hospitalizations.3

References

References

  1. "Cryo-laser and cryo-sclerotherapy guided by augmented reality for telangiectasias, feeder, and small varicose vein treatment–The CLaCS technique white paper report". scholar.google.com. Retrieved 2024-07-10.
  2. Miyake, Roberto Kasuo; Chi, Yung-Wei; Franklin, Ian J.; Gianesini, Sergio (2020). "State of the art on cryo-laser cryo-sclerotherapy in lower limb venous aesthetic treatment". Journal of Vascular Surgery. Venous and Lymphatic Disorders. 8 (5): 893–895. doi:10.1016/j.jvsv.2020.01.003. ISSN 2213-3348. PMID 32179040.
  3. Miyake, Hiroshi; Miyake, Kasuo; Duarte, Flávio; Kikuchi, Rodrigo (2008). "Pequenas Varizes e Telangiectasias" [Small Varicose Veins and Telangiectasias]. Doenças Vasculares Periféricas (in Portuguese). 2 (4 ed.). Rio de Janeiro, RJ: Guanabara Koogan S.A.: 1769–1795. ISBN 9788527714600.
  4. "Reality, only better, December 8th". The Economist. ISSN 0013-0613. Retrieved 2024-07-10.
  5. Miyake, RK; Zeman, HD; Duarte, FH; Kikuchi, R; Ramacciotti, E; Lovhoiden, G; Vrancken, C (2014-01-24). "Vein imaging: a new method of near infrared imaging, where a processed image is projected onto the skin for the enhancement of vein treatment". Dermatol Surg. 32 (8): 1031–8. doi:10.1111/j.1524-4725.2006.32226.x. PMID 16918565. S2CID 8872471.