Article · Wikipedia archive · Last revised Aug 5, 2026

Cibenzoline

Cibenzoline is a Class Ia antiarrhythmic drug.

Last revised
Aug 5, 2026
Read time
≈ 1 min
Length
141 w
Citations
2
Source
Cibenzoline
source ↗
Names
IUPAC name
2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1H-imidazole
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.053.122
KEGG
UNII
  • InChI=1/C18H18N2/c1-3-7-14(8-4-1)18(15-9-5-2-6-10-15)13-16(18)17-19-11-12-20-17/h1-10,16H,11-13H2,(H,19,20)
    Key: IPOBOOXFSRWSHL-UHFFFAOYAC
  • N\1=C(\NCC/1)C4CC4(c2ccccc2)c3ccccc3
Properties
C18H18N2
Molar mass 262.35 g/mol
Pharmacology
C01BG07 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Cibenzoline (or cifenline) is a Class Ia antiarrhythmic drug.12

Pituxate & Ecipramidil are other gem-diphenyl cyclopropanyl drugs.

References

References

  1. Harron, Dean W. G.; Brogden, Rex N.; Faulds, Diana; Fitton, Andrew (1992-05-01). "Cibenzoline". Drugs. 43 (5): 734–759. doi:10.2165/00003495-199243050-00008. ISSN 1179-1950.
  2. Miura, Dennis S.; Keren, Gad; Torres, Vilma; Butler, Brenda; Aogaichi, Keiko; Somberg, John C. (1985-04-01). "Antiarrhythmic effects of cibenzoline". American Heart Journal. 109 (4): 827–833. doi:10.1016/0002-8703(85)90646-5. ISSN 0002-8703.