CDYL2

CDYL2
Identifiers
Aliases	CDYL2, PCCP1, chromodomain protein, Y-like 2, chromodomain Y like 2
External IDs	MGI: 1923046; HomoloGene: 41779; GeneCards: CDYL2; OMA:CDYL2 - orthologs
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2MJ8, 4HAE, 5JJZ
Gene location (Human)
Chr.	Chromosome 16 (human)
End	80,804,598 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	117,459,730 bp
RNA expression pattern
	Top expressed in
	cerebellar vermis; ; placenta; ; mucosa of ileum; ; middle temporal gyrus; ; Brodmann area 46; ; testicle; ; Brodmann area 23; ; pancreatic epithelial cell; ; jejunal mucosa; ; tail of epididymis;
	Top expressed in
	blastocyst; ; morula; ; spermatid; ; granulocyte; ; embryo; ; zygote; ; right kidney; ; seminiferous tubule; ; embryo; ; thymus;
	More reference expression data
	n/a
Gene ontology
Molecular function	catalytic activity; protein binding; methylated histone binding; transcription corepressor activity;
Cellular component	nucleus;
Biological process	metabolism; negative regulation of nucleic acid-templated transcription;
	Sources:Amigo / QuickGO
Orthologs
	124359
	75796
	ENSG00000166446
	ENSMUSG00000031758
	Q8N8U2
	Q9D5D8
	NM_152342
	NM_029441
	NP_689555
	NP_083717
	Wikidata
View/Edit Human	View/Edit Mouse

Chromodomain protein, Y-like 2 is a protein in humans that is encoded by the CDYL2 gene. It localizes to the nucleus, where it acts as a chromatin reader recognizing trimethylation of Histone H3 lysine 9 and repressing transcription.⁵

References

GRCh38: Ensembl release 89: ENSG00000166446 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000031758 – Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: Chromodomain protein, Y-like 2". Retrieved 2013-01-13.

External links

PDBe-KB provides an overview of all the structure information available in the PDB for Human Chromodomain Y-like protein 2 (CDYL2)

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000166446 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000031758 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Chromodomain protein, Y-like 2". Retrieved 2013-01-13.

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