CALML3

CALML3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1GGZ
Identifiers
Aliases	CALML3, CLP, calmodulin like 3
External IDs	OMIM: 114184; MGI: 1917655; HomoloGene: 133078; GeneCards: CALML3; OMA:CALML3 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	5,526,771 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	3,854,316 bp
RNA expression pattern
	Top expressed in
	gums; ; gingival epithelium; ; vulva; ; skin of arm; ; mucosa of pharynx; ; oral cavity; ; skin of leg; ; skin of abdomen; ; cervix epithelium; ; hair follicle;
	Top expressed in
	conjunctival fornix; ; lip; ; esophagus; ; cornea; ; skin of external ear; ; ciliary body; ; skin of back; ; umbilical cord; ; parotid gland; ; skin of abdomen;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	metal ion binding; protein binding; calcium ion binding;
Cellular component	extracellular exosome; nucleus;
Biological process	calcium-mediated signaling; spindle pole body organization;
	Sources:Amigo / QuickGO
Orthologs
	810
	70405
	ENSG00000178363
	ENSMUSG00000063130
	P27482
	Q9D6P8
	NM_005185
	NM_027416
	NP_005176
	NP_081692
	Wikidata
View/Edit Human	View/Edit Mouse

Calmodulin-like protein 3 is a protein that in humans is encoded by the CALML3 gene.⁵⁶

References

GRCh38: Ensembl release 89: ENSG00000178363 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000063130 – Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Koller M, Strehler EE (May 1993). "Functional analysis of the promoters of the human CaMIII calmodulin gene and of the intronless gene coding for a calmodulin-like protein". Biochim Biophys Acta. 1163 (1): 1–9. doi:10.1016/0167-4838(93)90271-R. PMID 8476923.
"Entrez Gene: CALML3 calmodulin-like 3".

External links

Human CALML3 genome location and CALML3 gene details page in the UCSC Genome Browser.

Further reading

Rhyner JA, Koller M, Durussel-Gerber I, et al. (1993). "Characterization of the human calmodulin-like protein expressed in Escherichia coli". Biochemistry. 31 (51): 12826–32. doi:10.1021/bi00166a017. PMID 1334432.
Yaswen P, Smoll A, Peehl DM, et al. (1990). "Down-regulation of a calmodulin-related gene during transformation of human mammary epithelial cells". Proc. Natl. Acad. Sci. U.S.A. 87 (19): 7360–4. Bibcode:1990PNAS...87.7360Y. doi:10.1073/pnas.87.19.7360. PMC 54746. PMID 2217169.
Koller M, Strehler EE (1988). "Characterization of an intronless human calmodulin-like pseudogene". FEBS Lett. 239 (1): 121–8. doi:10.1016/0014-5793(88)80558-1. PMID 3181418. S2CID 29139707.
Berchtold MW, Koller M, Egli R, et al. (1993). "Localization of the intronless gene coding for calmodulin-like protein CLP to human chromosome 10p13-ter". Hum. Genet. 90 (5): 496–500. doi:10.1007/BF00217447. PMID 8428750. S2CID 41567243.
Durussel I, Rhyner JA, Strehler EE, Cox JA (1993). "Cation binding and conformation of human calmodulin-like protein". Biochemistry. 32 (23): 6089–94. doi:10.1021/bi00074a021. PMID 8507643.
Rogers MS, Strehler EE (2001). "The tumor-sensitive calmodulin-like protein is a specific light chain of human unconventional myosin X." J. Biol. Chem. 276 (15): 12182–9. doi:10.1074/jbc.M010056200. PMID 11278607.
Rogers MS, Kobayashi T, Pittelkow MR, Strehler EE (2001). "Human calmodulin-like protein is an epithelial-specific protein regulated during keratinocyte differentiation". Exp. Cell Res. 267 (2): 216–24. doi:10.1006/excr.2001.5254. PMID 11426940.
Han BG, Han M, Sui H, et al. (2002). "Crystal structure of human calmodulin-like protein: insights into its functional role". FEBS Lett. 521 (1–3): 24–30. doi:10.1016/S0014-5793(02)02780-1. PMID 12067719. S2CID 20087760.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. Bibcode:2004Natur.429..375D. doi:10.1038/nature02462. PMID 15164054.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Bennett RD, Mauer AS, Strehler EE (2007). "Calmodulin-like protein increases filopodia-dependent cell motility via up-regulation of myosin-10". J. Biol. Chem. 282 (5): 3205–12. doi:10.1074/jbc.M607174200. PMID 17130134.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000178363 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000063130 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8476923-5] Koller M, Strehler EE (May 1993). "Functional analysis of the promoters of the human CaMIII calmodulin gene and of the intronless gene coding for a calmodulin-like protein". Biochim Biophys Acta. 1163 (1): 1–9. doi:10.1016/0167-4838(93)90271-R. PMID 8476923.

[entrez-6] "Entrez Gene: CALML3 calmodulin-like 3".

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