Aspergillusene

Aspergillusene A

Aspergillusene B

Aspergillusene C

Aspergillusenes are a group of chemical compounds first isolated from a strain of sea fan-derived fungus Aspergillus sydowii.¹ They are sesquiterpenes of the bisabolane-type.²

A laboratory synthesis of aspergillusene B was reported in 2020.³

References

Trisuwan, K; Rukachaisirikul, V; Kaewpet, M; Phongpaichit, S; Hutadilok-Towatana, N; Preedanon, S; Sakayaroj, J (2013-08-12). "Sesquiterpene and xanthone derivatives from the sea fan-derived fungus Aspergillus sydowii PSU-F154". J Nat Prod. 74 (7): 1663–7. doi:10.1021/np200374j. PMID 21718031.
Liu, Nianzhen; Peng, Shuai; Yang, Jie; Cong, Ziwen; Lin, Xiuping; Liao, Shengrong; Yang, Bin; Zhou, Xuefeng; Zhou, Xiaojiang; Liu, Yonghong; Wang, Junfeng (2019). "Structurally diverse sesquiterpenoids and polyketides from a sponge-associated fungus Aspergillus sydowii SCSIO41301". Fitoterapia. 135: 27–32. doi:10.1016/j.fitote.2019.03.031. PMID 30946944. S2CID 96432484.
Grabovyi, Gennadii A.; Bhatti, Aisha; Mohr, Justin T. (2020). "Total Synthesis of Benzofuran-Based Aspergillusene B via Halogenative Aromatization of Enones". Organic Letters. 22 (11): 4196–4200. doi:10.1021/acs.orglett.0c01259. PMID 32437168. S2CID 218831928.

[1] Trisuwan, K; Rukachaisirikul, V; Kaewpet, M; Phongpaichit, S; Hutadilok-Towatana, N; Preedanon, S; Sakayaroj, J (2013-08-12). "Sesquiterpene and xanthone derivatives from the sea fan-derived fungus Aspergillus sydowii PSU-F154". J Nat Prod. 74 (7): 1663–7. doi:10.1021/np200374j. PMID 21718031.

[2] Liu, Nianzhen; Peng, Shuai; Yang, Jie; Cong, Ziwen; Lin, Xiuping; Liao, Shengrong; Yang, Bin; Zhou, Xuefeng; Zhou, Xiaojiang; Liu, Yonghong; Wang, Junfeng (2019). "Structurally diverse sesquiterpenoids and polyketides from a sponge-associated fungus Aspergillus sydowii SCSIO41301". Fitoterapia. 135: 27–32. doi:10.1016/j.fitote.2019.03.031. PMID 30946944. S2CID 96432484.

[3] Grabovyi, Gennadii A.; Bhatti, Aisha; Mohr, Justin T. (2020). "Total Synthesis of Benzofuran-Based Aspergillusene B via Halogenative Aromatization of Enones". Organic Letters. 22 (11): 4196–4200. doi:10.1021/acs.orglett.0c01259. PMID 32437168. S2CID 218831928.

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