Article · Wikipedia archive · Last revised Jul 3, 2026

ACTL8

Actin-like 8 is a protein in humans that is encoded by the ACTL8 gene. It is a protein that is used in making the intracellular architecture of cells. ACTL8 expression is significantly upregulated in gastric cancer cells and is strongly associated with negative patient outcomes.

Last revised
Jul 3, 2026
Read time
≈ 1 min
Length
209 w
Citations
6
Source
ACTL8
Identifiers
AliasesACTL8, CT57, actin like 8
External IDsHomoloGene: 57127; GeneCards: ACTL8; OMA:ACTL8 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_030812

n/a

RefSeq (protein)

NP_110439

n/a

Location (UCSC)Chr 1: 17.76 – 17.83 Mbn/a
PubMed search2n/a
Wikidata
View/Edit Human

Actin-like 8 is a protein in humans that is encoded by the ACTL8 gene. It is a protein that is used in making the intracellular architecture of cells.3 ACTL8 expression is significantly upregulated in gastric cancer cells and is strongly associated with negative patient outcomes.4

References

References

  1. GRCh38: Ensembl release 89: ENSG00000117148Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. "Entrez Gene: Actin-like 8". Retrieved 2012-11-02.
  4. Yu W, Zhang Q, Ali M, Chen B, Sun Q, Wang D (October 2024). "ACTL8 Promotes the Progression of Gastric Cancer Through PI3K/AKT/mTOR Signaling Pathway". Digestive Diseases and Sciences. 69 (10): 3786–3798. doi:10.1007/s10620-024-08649-6. PMC 11489201. PMID 39322809.
External links