Article · Wikipedia archive · Last revised Jul 17, 2026

4-APB

4-(2-Aminopropyl)benzofuran (4-APB) is a monoamine releasing agent and novel designer drug of the benzofuran family. It acts as a serotonin–norepinephrine–dopamine releasing agent (SNDRA). The drug was first detected, in Europe, by 2011.

Last revised
Jul 17, 2026
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≈ 1 min
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Citations
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4-APB
Clinical data
Other names4-(2-Aminopropyl)benzofuran; 4-APB
Drug classSerotonin–norepinephrine–dopamine releasing agent12
Identifiers
  • 1-(1-benzofuran-4-yl)propan-2-amine
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC11H13NO
Molar mass175.231 g·mol−1
3D model (JSmol)
  • CC(CC1=C2C=COC2=CC=C1)N
  • InChI=1S/C11H13NO/c1-8(12)7-9-3-2-4-11-10(9)5-6-13-11/h2-6,8H,7,12H2,1H3
  • Key:XROLBZOMVNMIFN-UHFFFAOYSA-N

4-(2-Aminopropyl)benzofuran (4-APB) is a monoamine releasing agent and novel designer drug of the benzofuran family.34521 It acts as a serotonin–norepinephrine–dopamine releasing agent (SNDRA).12 The drug was first detected, in Europe, by 2011.3

See also

See also

References

References

  1. Rickli A, Kopf S, Hoener MC, Liechti ME (July 2015). "Pharmacological profile of novel psychoactive benzofurans". Br J Pharmacol. 172 (13): 3412–3425. doi:10.1111/bph.13128. PMC 4500375. PMID 25765500.
  2. Simmler LD, Liechti ME (2018). "Pharmacology of MDMA- and Amphetamine-Like New Psychoactive Substances". Handb Exp Pharmacol. Handbook of Experimental Pharmacology. 252: 143–164. doi:10.1007/164_2018_113. ISBN 978-3-030-10560-0. PMID 29633178.
  3. "Europol 2011 Annual Report on the implementation of Council Decision 2005/387/JHA". Europol. 23 October 2018. Retrieved 27 February 2025.
  4. Stanczuk A, Morris N, Gardner EA, Kavanagh P (April 2013). "Identification of (2-aminopropyl)benzofuran (APB) phenyl ring positional isomers in internet purchased products". Drug Test Anal. 5 (4): 270–276. doi:10.1002/dta.1451. PMID 23349125.
  5. Casale JF, Hays PA (2012). "The characterization of 6-(2-aminopropyl) benzofuran and differentiation from its 4-, 5-, and 7-positional analogues" (PDF). Microgram Journal. 9 (2): 61–74.
External links