Article · Wikipedia archive · Last revised Aug 2, 2026

2,3-Methylenedioxymethamphetamine

2,3-Methylenedioxymethamphetamine, also known as 2,3-MDMA or ORTHO-MDMA, is a positional isomer of the recreational drug 3,4-MDMA. It is a monoamine transporter (MAT) substrate and inhibitor similarly to 3,4-MDMA. However, while showing similar potency at the norepinephrine transporter (NET), 2,3-MDMA is less potent at the serotonin transporter (SERT). 2,3-MDMA has not been encountered as a recreational or designer drug.

Last revised
Aug 2, 2026
Read time
≈ 1 min
Length
175 w
Citations
4
Source
Wikipedia ↗
ORTHO-MDMA
Clinical data
Other names2,3-MDMA; 2,3-Methylenedioxy-N-methylamphetamine; ORTHO-MDMA
ATC code
  • None
Identifiers
  • 1-(1,3-Benzodioxol-4-yl)-N-methylpropan-2-amine
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC11H15NO2
Molar mass193.246 g·mol−1
3D model (JSmol)
  • CC(CC1=C2C(=CC=C1)OCO2)NC
  • InChI=1S/C11H15NO2/c1-8(12-2)6-9-4-3-5-10-11(9)14-7-13-10/h3-5,8,12H,6-7H2,1-2H3/t8-/m0/s1 checkY
  • Key:RTZIIFGBTSUSEL-QMMMGPOBSA-N checkY

2,3-Methylenedioxymethamphetamine, also known as 2,3-MDMA or ORTHO-MDMA, is a positional isomer of the recreational drug 3,4-MDMA (commonly known as Ecstasy or Molly).1 It is a monoamine transporter (MAT) substrate and inhibitor similarly to 3,4-MDMA.2 However, while showing similar potency at the norepinephrine transporter (NET), 2,3-MDMA is less potent at the serotonin transporter (SERT).2 2,3-MDMA has not been encountered as a recreational or designer drug.2

See also

See also

References

References

External links